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Chronic metabolic acidosis enhances NHE-3 protein abundance and transport activity in the rat thick ascending limb by increasing NHE-3 mRNA.

Chronic metabolic acidosis (CMA) is associated with an adaptive increase in the bicarbonate absorptive capacity of the rat medullary thick ascending limb (MTAL). To specify whether NHE-3, the apical MTAL Na/H exchanger, is involved in this adaptation, NHE-3 mRNA was quantified by a competitive RT-PC...

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書誌詳細
主要な著者: Laghmani, K, Borensztein, P, Ambühl, P, Froissart, M, Bichara, M, Moe, O W, Alpern, R J, Paillard, M
フォーマット: Artigo
言語:Inglês
出版事項: 1997
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC507763/
https://ncbi.nlm.nih.gov/pubmed/9011571
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