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Increased expression of insulin/insulin-like growth factor-I hybrid receptors in skeletal muscle of noninsulin-dependent diabetes mellitus subjects.

Insulin receptors (IR) and IGF-I receptors (IGF-IR) have been shown to form hybrid receptors in tissues coexpressing both molecules. To date there is no information about the distribution of hybrids in tissues of normal or diabetic subjects. We developed a microwell-based immunoassay to quantitate h...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Federici, M, Zucaro, L, Porzio, O, Massoud, R, Borboni, P, Lauro, D, Sesti, G
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507756/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8981937/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119117
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