HLA-B27 heavy chains contribute to spontaneous inflammatory disease in B27/human beta2-microglobulin (beta2m) double transgenic mice with disrupted mouse beta2m.

MHC class I allele, HLA-B27, is strongly associated with a group of human diseases called spondyloarthropathies. Some of these diseases have an onset after an enteric or genitourinary infection. In the present study, we describe spontaneous disease in HLA-B27 transgenic mice where endogenous beta2-m...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Khare, S D, Hansen, J, Luthra, H S, David, C S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507739/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8981920/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119100
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