Proliferation induced by keratinocyte growth factor enhances in vivo retroviral-mediated gene transfer to mouse hepatocytes.

Retroviral gene transfer to liver without prior injury has not yet been accomplished. We hypothesized that recombinant human keratinocyte growth factor would stimulate proliferation of hepatocytes and allow for efficient in vivo gene transfer with high titer murine Moloney retroviral vectors. This r...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Bosch, A, McCray, P B, Chang, S M, Ulich, T R, Simonet, W S, Jolly, D J, Davidson, B L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1996
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507730/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8981911/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119091
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