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Melanosis and associated tumors in transgenic mice.

Melanosis was found to various extents in a wide array of tissues of all 23 autopsied mice whose transgene consisted of the tyrosinase promoter fused to the simian virus 40 early-region oncogenic sequences. Pigmentation in a given animal was attributable to any or all of the following; an increase i...

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Detalles Bibliográficos
Publicado en:Proc Natl Acad Sci U S A
Principais autores: Klein-Szanto, A, Bradl, M, Porter, S, Mintz, B
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 1991
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Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50771/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1846037/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.1.169
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