Complex Pattern of Resistance-Associated Substitutions of Hepatitis C Virus after Daclatasvir/Asunaprevir Treatment Failure

BACKGROUNDS & AIMS: We aimed to clarify the characteristics of resistance-associated substitutions (RASs) after treatment failure with NS5A inhibitor, daclatasvir (DCV) in combination with NS3/4A inhibitor, asunaprevir (ASV), in patients with chronic hepatitis C virus genotype 1b infection. METH...

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Publicado en:PLoS One
Main Authors: Itakura, Jun, Kurosaki, Masayuki, Hasebe, Chitomi, Osaki, Yukio, Joko, Kouji, Yagisawa, Hitoshi, Sakita, Shinya, Okushin, Hiroaki, Satou, Takashi, Hisai, Hiroyuki, Abe, Takehiko, Tsuji, Keiji, Tamada, Takashi, Kobashi, Haruhiko, Mitsuda, Akeri, Ide, Yasushi, Ogawa, Chikara, Tsuruta, Syotaro, Takaguchi, Kouichi, Murakawa, Miyako, Asahina, Yasuhiro, Enomoto, Nobuyuki, Izumi, Namiki
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
Assuntos:
Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5077083/
https://ncbi.nlm.nih.gov/pubmed/27776192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0165339
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