Impact of ornithine phenylacetate (OCR-002) in lowering plasma ammonia after upper gastrointestinal bleeding in cirrhotic patients

BACKGROUND: Ornithine phenylacetate (OP) has been proven effective in lowering ammonia plasma levels in animals, and to be well tolerated in cirrhotic patients. A trial to assess OP efficacy in lowering plasma ammonia levels versus placebo in cirrhotic patients after an upper gastrointestinal bleedi...

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Bibliografische gegevens
Gepubliceerd in:Therap Adv Gastroenterol
Hoofdauteurs: Ventura-Cots, Meritxell, Concepción, Mar, Arranz, José Antonio, Simón-Talero, Macarena, Torrens, Maria, Blanco-Grau, Albert, Fuentes, Inma, Suñé, Pilar, Alvarado-Tapias, Edilmar, Gely, Cristina, Roman, Eva, Mínguez, Beatriz, Soriano, German, Genescà, Joan, Córdoba, Juan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: SAGE Publications 2016
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Original Research
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076769/
https://ncbi.nlm.nih.gov/pubmed/27803737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1756283X16658252
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