Association Studies and Direct DNA Sequencing Implicate Genetic Susceptibility Loci in the Etiology of Nonsyndromic Orofacial Clefts in Sub-Saharan African Populations

Orofacial clefts (OFCs) are congenital dysmorphologies of the human face and oral cavity, with a global incidence of 1 per 700 live births. These anomalies exhibit a multifactorial pattern of inheritance, with genetic and environmental factors both playing crucial roles. Many loci have been implicat...

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Détails bibliographiques
Publié dans:J Dent Res
Auteurs principaux: Gowans, L.J.J., Adeyemo, W.L., Eshete, M., Mossey, P.A., Busch, T., Aregbesola, B., Donkor, P., Arthur, F.K.N., Bello, S.A., Martinez, A., Li, M., Augustine-Akpan, E.A., Deressa, W., Twumasi, P., Olutayo, J., Deribew, M., Agbenorku, P., Oti, A.A., Braimah, R., Plange-Rhule, G., Gesses, M., Obiri-Yeboah, S., Oseni, G.O., Olaitan, P.B., Abdur-Rahman, L., Abate, F., Hailu, T., Gravem, P., Ogunlewe, M.O., Buxó, C.J., Marazita, M.L., Adeyemo, A.A., Murray, J.C., Butali, A.
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2016
Sujets:
Research Reports
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076758/
https://ncbi.nlm.nih.gov/pubmed/27369588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0022034516657003
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