Characterization of Gonadotrope Secretoproteome Identifies Neurosecretory Protein VGF-derived Peptide Suppression of Follicle-stimulating Hormone Gene Expression

Reproductive function is controlled by the pulsatile release of hypothalamic gonadotropin-releasing hormone (GnRH), which regulates the expression of the gonadotropins luteinizing hormone and FSH in pituitary gonadotropes. Paradoxically, Fshb gene expression is maximally induced at lower frequency G...

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Vydáno v:J Biol Chem
Hlavní autoři: Choi, Soon Gang, Wang, Qian, Jia, Jingjing, Chikina, Maria, Pincas, Hanna, Dolios, Georgia, Sasaki, Kazuki, Wang, Rong, Minamino, Naoto, Salton, Stephen R. J., Sealfon, Stuart C.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Gene Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076536/
https://ncbi.nlm.nih.gov/pubmed/27466366
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.740365
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