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Orai1 and TRPC1 Proteins Co-localize with Ca(V)1.2 Channels to Form a Signal Complex in Vascular Smooth Muscle Cells

Voltage-dependent Ca(V)1.2 L-type Ca(2+) channels (LTCC) are the main route for calcium entry in vascular smooth muscle cells (VSMC). Several studies have also determined the relevant role of store-operated Ca(2+) channels (SOCC) in vascular tone regulation. Nevertheless, the role of Orai1- and TRPC...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Biol Chem
Hauptverfasser: Ávila-Medina, Javier, Calderón-Sánchez, Eva, González-Rodríguez, Patricia, Monje-Quiroga, Francisco, Rosado, Juan Antonio, Castellano, Antonio, Ordóñez, Antonio, Smani, Tarik
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076523/
https://ncbi.nlm.nih.gov/pubmed/27535226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.742171
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