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Corticotropin-releasing hormone excites adrenocorticotropin-secreting human pituitary adenoma cells by activating a nonselective cation current.

The mechanisms of corticotropin-releasing hormone (CRH) induced excitation of ACTH-secreting adenoma cells were investigated using the perforated whole-cell clamp technique and intracellular Ca2+ concentration ([Ca2+]i) measurement. CRH depolarized ACTH-secreting adenoma cells by activating a nonsel...

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Bibliografische gegevens
Gepubliceerd in:J Clin Invest
Hoofdauteurs: Takano, K, Yasufuku-Takano, J, Teramoto, A, Fujita, T
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Clinical Investigation 1996
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507647/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8903322/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI119008
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