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Expression and significance of TGF-β1/Smad signaling pathway in children with IgA nephropathy

BACKGROUND: IgA nephropathy (IgAN) exhibits an indolent but slowly progressive course, and about 30% of children with IgAN are found to deteriorate to end-stage renal failure characterized by overaccumulation of extracellular matrix, diffuse glomerular sclerosis, and tubulointerstitial fibrosis. The...

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Publicat a:World J Pediatr
Autors principals: Wu, Wei, Jiang, Xiao-Yun, Zhang, Qiao-Ling, Mo, Ying, Sun, Liang-Zhong, Chen, Shu-Mei
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076469/
https://ncbi.nlm.nih.gov/pubmed/19693466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12519-009-0040-3
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