Age-associated repression of type 1 inositol 1, 4, 5-triphosphate receptor impairs muscle regeneration

Skeletal muscle mass and power decrease with age, leading to impairment of mobility and metabolism in the elderly. Ca(2+) signaling is crucial for myoblast differentiation as well as muscle contraction through activation of transcription factors and Ca(2+)-dependent kinases and phosphatases. Ca(2+)...

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Détails bibliographiques
Publié dans:Aging (Albany NY)
Auteurs principaux: Choi, Jeong Yi, Hwang, Chae Young, Lee, Bora, Lee, Seung-Min, Bahn, Young Jae, Lee, Kwang-Pyo, Kang, Moonkyung, Kim, Yeon-Soo, Woo, Sun-Hee, Lim, Jae-Young, Kim, Eunhee, Kwon, Ki-Sun
Format: Artigo
Langue:Inglês
Publié: Impact Journals LLC 2016
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076452/
https://ncbi.nlm.nih.gov/pubmed/27658230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101039
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