Mechanisms of impaired beta-adrenoceptor-induced airway relaxation by interleukin-1beta in vivo in the rat.

We studied the in vivo mechanism of beta-adrenergic receptor (beta-AR) hyporesponsiveness induced by intratracheal instillation of interleukin-1beta (IL-1beta, 500 U) in Brown-Norway rats. Tracheal and bronchial smooth muscle responses were measured under isometric conditions ex vivo. Contractile re...

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Εκδόθηκε σε:	J Clin Invest
Κύριοι συγγραφείς:	Koto, H, Mak, J C, Haddad, E B, Xu, W B, Salmon, M, Barnes, P J, Chung, K F
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	American Society for Clinical Investigation 1996
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507616/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8878428/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118977
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