Soluble human CD4 elicits an antibody response in rhesus monkeys that inhibits simian immunodeficiency virus replication.

Rhesus monkeys infected with the simian immunodeficiency virus of macaques (SIVmac) demonstrate significant virologic and clinical improvement as a result of treatment with human recombinant soluble CD4 (rsCD4). We show that human rsCD4 does not efficiently inhibit SIVmac replication in bone marrow...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Watanabe, M, Chen, Z W, Tsubota, H, Lord, C I, Levine, C G, Letvin, N L
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1991
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50761/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1986356/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.1.120
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