Intestinal brush-border Na(+)/H(+) exchanger-3 drives H(+)-coupled iron absorption in the mouse

Divalent metal-ion transporter-1 (DMT1), the principal mechanism by which nonheme iron is taken up at the intestinal brush border, is energized by the H(+)-electrochemical potential gradient. The provenance of the H(+) gradient in vivo is unknown, so we have explored a role for brush-border Na(+)/H(...

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Detalles Bibliográficos
Publicado en:Am J Physiol Gastrointest Liver Physiol
Autores principales: Shawki, Ali, Engevik, Melinda A., Kim, Robert S., Knight, Patrick B., Baik, Rusty A., Anthony, Sarah R., Worrell, Roger T., Shull, Gary E., Mackenzie, Bryan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2016
Materias:
Nutrient Sensing, Nutrition, and Metabolism
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5076011/
https://ncbi.nlm.nih.gov/pubmed/27390324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00167.2016
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