Tumor escape from immune recognition: lethal recurrent melanoma in a patient associated with downregulation of the peptide transporter protein TAP-1 and loss of expression of the immunodominant MART-1/Melan-A antigen.

In the last few years, mutiple protein target antigens for immunorecognition by T cells have been identified on human melanoma. How melanoma lesions escape from functional antigen-specific immune recognition remains poorly understood. We have identified the concomitant loss of the immunodominant T c...

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Detalhes bibliográficos
Main Authors: Maeurer, M J, Gollin, S M, Martin, D, Swaney, W, Bryant, J, Castelli, C, Robbins, P, Parmiani, G, Storkus, W J, Lotze, M T
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC507597/
https://ncbi.nlm.nih.gov/pubmed/8833913
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