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Antibodies against CD14 protect primates from endotoxin-induced shock.

Lipopolysaccharide (LPS), residing in the outer membrane of all gram-negative bacteria, is considered a major initiating factor of the gram-negative septic shock syndrome in humans. LPS forms a complex with the LPS binding protein (LBP) in plasma, and LPS-LBP complexes engage a specific receptor, CD...

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Udgivet i:J Clin Invest
Principais autores: Leturcq, D J, Moriarty, A M, Talbott, G, Winn, R K, Martin, T R, Ulevitch, R J
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 1996
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507584/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8833900/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118945
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