Antiplasmodial Activity Is an Ancient and Conserved Feature of Tick Defensins

Ancestral sequence reconstruction has been widely used to test evolution-based hypotheses. The genome of the European tick vector, Ixodes ricinus, encodes for defensin peptides with diverse antimicrobial activities against distantly related pathogens. These pathogens include fungi, Gram-negative, an...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Cabezas-Cruz, Alejandro, Tonk, Miray, Bouchut, Anne, Pierrot, Christine, Pierce, Raymond J., Kotsyfakis, Michalis, Rahnamaeian, Mohammad, Vilcinskas, Andreas, Khalife, Jamal, Valdés, James J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075766/
https://ncbi.nlm.nih.gov/pubmed/27822206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2016.01682
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