Plasmid-Based Generation of Induced Neural Stem Cells from Adult Human Fibroblasts

Direct reprogramming from somatic to neural cell types has become an alternative to induced pluripotent stem cells. Most protocols employ viral expression systems, posing the risk of random genomic integration. Recent developments led to plasmid-based protocols, lowering this risk. However, these pr...

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Udgivet i:Front Cell Neurosci
Main Authors: Capetian, Philipp, Azmitia, Luis, Pauly, Martje G., Krajka, Victor, Stengel, Felix, Bernhardi, Eva-Maria, Klett, Mariana, Meier, Britta, Seibler, Philip, Stanslowsky, Nancy, Moser, Andreas, Knopp, Andreas, Gillessen-Kaesbach, Gabriele, Nikkhah, Guido, Wegner, Florian, Döbrössy, Máté, Klein, Christine
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2016
Fag:
Neuroscience
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075569/
https://ncbi.nlm.nih.gov/pubmed/27822179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2016.00245
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