Oral administration of a non-absorbable plant cell-expressed recombinant anti-TNF fusion protein induces immunomodulatory effects and alleviates nonalcoholic steatohepatitis

AIM: To evaluate the immunomodulatory effect of oral administration of PRX-106 in the high-fat diet model. METHODS: For 22 wk, C57BL/6 HFD-fed mice received daily oral treatments with BY-2 cells expressing recombinant anti-tumor necrosis factor alpha fusion protein (PRX-106). Mice were followed for...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:World J Gastroenterol
Egile Nagusiak: Ilan, Yaron, Ben Ya'acov, Ami, Shabbat, Yehudit, Gingis-Velitski, Svetlana, Almon, Einat, Shaaltiel, Yoseph
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Baishideng Publishing Group Inc 2016
Gaiak:
Basic Study
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075550/
https://ncbi.nlm.nih.gov/pubmed/27818591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3748/wjg.v22.i39.8760
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