HIV infection--induced posttranslational modification of T cell signaling molecules associated with disease progression.

In attempt to elucidate the mechanism of the HIV infection induced T cell unresponsiveness, we studied signal-transducing molecules proximal to the T cell receptor (TCR) in T lymphocytes of HIV-infected individuals. Total amounts of protein tyrosine kinases (PTKs) Lck, Fyn, and ZAP-70 and the zeta c...

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Detalhes bibliográficos
Main Authors: Stefanová, I, Saville, M W, Peters, C, Cleghorn, F R, Schwartz, D, Venzon, D J, Weinhold, K J, Jack, N, Bartholomew, C, Blattner, W A, Yarchoan, R, Bolen, J B, Horak, I D
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC507554/
https://ncbi.nlm.nih.gov/pubmed/8823293
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