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Drug delivery into the cochlear apex: Improved control to sequentially affect finely spaced regions along the entire length of the cochlear spiral

BACKGROUND: Administering pharmaceuticals to the scala tympani of the inner ear is a common approach to study cochlear physiology and mechanics. We present here a novel method for in vivo drug delivery in a controlled manner to sealed ears. NEW METHOD: Injections of ototoxic solutions were applied f...

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Detalhes bibliográficos
Publicado no:J Neurosci Methods
Main Authors: Lichtenhan, JT, Hartsock, J, Dornhoffer, JR, Donovan, KM, Salt, AN
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075496/
https://ncbi.nlm.nih.gov/pubmed/27506463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneumeth.2016.08.005
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