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Identification of targets of leptin action in rat hypothalamus.

The hypothesis that leptin (OB protein) acts in the hypothalamus to reduce food intake and body weight is based primarily on evidence from leptin-deficient, ob/ob mice. To investigate whether leptin exerts similar effects in normal animals, we administered leptin intracerebroventricularly (icv) to L...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Schwartz, M W, Seeley, R J, Campfield, L A, Burn, P, Baskin, D G
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1996
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507530/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8787671/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118891
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