Resistance of Transmitted Founder HIV-1 to IFITM-Mediated Restriction

Interferon-induced transmembrane proteins (IFITMs) restrict the entry of diverse enveloped viruses through incompletely understood mechanisms. While IFITMs are reported to inhibit HIV-1, their in vivo relevance is unclear. We show that IFITM sensitivity of HIV-1 strains is determined by the co-recep...

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Detalhes bibliográficos
Publicado no:Cell Host Microbe
Main Authors: Foster, Toshana L., Wilson, Harry, Iyer, Shilpa S., Coss, Karen, Doores, Katie, Smith, Sarah, Kellam, Paul, Finzi, Andrés, Borrow, Persephone, Hahn, Beatrice H., Neil, Stuart J.D.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075283/
https://ncbi.nlm.nih.gov/pubmed/27640936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.08.006
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