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Facilitation of Hippocampal Kindling and Exacerbation of Kindled Seizures by Intra-CA1 Injection of Quinine: A Possible Role of Cx36 Gap Junctions

BACKGROUND: GABAergic interneurons in the hippocampal CA1 area are mutually communicated by gap junctions (GJs) composed of connexin36 (Cx36). We examined the role of Cx36 in CA1 in manifestation of kindled seizures and hippocampal kindling in rats. METHODS: Quinine, as the specific blocker of Cx36,...

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Bibliographische Detailangaben
Veröffentlicht in:Iran Biomed J
Hauptverfasser: Etemadi, Fatemeh, Sayyah, Mohammad, Pourbadie, Hamid Gholami, Babapour, Vahab
Format: Artigo
Sprache:Inglês
Veröffentlicht: Pasteur Institute 2016
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075139/
https://ncbi.nlm.nih.gov/pubmed/27108691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22045/ibj.2016.03
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