Correlation of Checkerboard Synergy Testing with Time-Kill Analysis and Clinical Outcomes of Extensively Drug-Resistant Acinetobacter baumannii Respiratory Infections

We tested 76 extensively drug-resistant (XDR) Acinetobacter baumannii isolates by the checkerboard method using only wells containing serum-achievable concentrations (SACs) of drugs. Checkerboard results were correlated by time-kill assay and clinical outcomes. Minocycline-colistin was the best comb...

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Udgivet i:Antimicrob Agents Chemother
Main Authors: Bremmer, Derek N., Bauer, Karri A., Pouch, Stephanie M., Thomas, Keelie, Smith, Debra, Goff, Debra A., Pancholi, Preeti, Balada-Llasat, Joan-Miquel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2016
Fag:
Clinical Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075101/
https://ncbi.nlm.nih.gov/pubmed/27527089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00981-16
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