Distinct Effects of T-705 (Favipiravir) and Ribavirin on Influenza Virus Replication and Viral RNA Synthesis

T-705 (favipiravir) is a new antiviral agent in advanced clinical development for influenza therapy. It is supposed to act as an alternative substrate for the viral polymerase, causing inhibition of viral RNA synthesis or virus mutagenesis. These mechanisms were also proposed for ribavirin, an estab...

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Detaylı Bibliyografya
Yayımlandı:Antimicrob Agents Chemother
Asıl Yazarlar: Vanderlinden, Evelien, Vrancken, Bram, Van Houdt, Jeroen, Rajwanshi, Vivek K., Gillemot, Sarah, Andrei, Graciela, Lemey, Philippe, Naesens, Lieve
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2016
Konular:
Antiviral Agents
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5075073/
https://ncbi.nlm.nih.gov/pubmed/27572398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01156-16
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