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High-Dose Cyclophosphamide is Effective Therapy for Pediatric Severe Aplastic Anemia

OBJECTIVE: Use of high-dose cyclophosphamide without hematopoietic stem cell transplant (HSCT) to treat severe aplastic anemia (SAA) has been controversial due to concern for increased infectious toxicity as compared to anti thymocyte globulin (ATG) and cyclosporine (CSA). As children often tolerate...

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Bibliographic Details
Published in:J Pediatr Hematol Oncol
Main Authors: Gamper, Christopher J., Takemoto, Clifford M., Chen, Allen R., Symons, Heather J., Loeb, David M., Casella, James F., Dezern, Amy E., King, Karen E., McGonigle, Andrea M., Jones, Richard J., Brodsky, Robert A.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074865/
https://ncbi.nlm.nih.gov/pubmed/27467367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPH.0000000000000647
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