High-Dose Cyclophosphamide is Effective Therapy for Pediatric Severe Aplastic Anemia

OBJECTIVE: Use of high-dose cyclophosphamide without hematopoietic stem cell transplant (HSCT) to treat severe aplastic anemia (SAA) has been controversial due to concern for increased infectious toxicity as compared to anti thymocyte globulin (ATG) and cyclosporine (CSA). As children often tolerate...

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Pubblicato in:J Pediatr Hematol Oncol
Autori principali: Gamper, Christopher J., Takemoto, Clifford M., Chen, Allen R., Symons, Heather J., Loeb, David M., Casella, James F., Dezern, Amy E., King, Karen E., McGonigle, Andrea M., Jones, Richard J., Brodsky, Robert A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074865/
https://ncbi.nlm.nih.gov/pubmed/27467367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPH.0000000000000647
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