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Captopril inhibits angiogenesis and slows the growth of experimental tumors in rats.

Captopril, an inhibitor of angiotensin converting enzyme, is widely used clinically to manage hypertension and congestive heart failure. Here captopril is shown to be an inhibitor of angiogenesis able to block neovascularization induced in the rat cornea. Captopril acted directly and specifically on...

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Detalhes bibliográficos
Main Authors: Volpert, O V, Ward, W F, Lingen, M W, Chesler, L, Solt, D B, Johnson, M D, Molteni, A, Polverini, P J, Bouck, N P
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC507476/
https://ncbi.nlm.nih.gov/pubmed/8698858
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