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Activation of antigen-induced lymphocyte proliferation by interleukin-15 without the mitogenic effect of interleukin-2 that may induce human immunodeficiency virus-1 expression.

The newly identified cytokine, IL-15 enhanced antigen-induced proliferation of PBMC obtained from HIV-1-seropositive subjects. When compared to IL-2 which enhanced both spontaneous and antigen-induced lymphocyte proliferative responses, IL-15 rarely increased spontaneous lymphocyte proliferation. Ad...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Clin Invest
Principais autores: Patki, A H, Quiñones-Mateu, M E, Dorazio, D, Yen-Lieberman, B, Boom, W H, Thomas, E K, Lederman, M M
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 1996
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507469/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8698851/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118831
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