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Desipramine Increases Genioglossus Activity and Reduces Upper Airway Collapsibility during Non-REM Sleep in Healthy Subjects

Rationale: Obstructive sleep apnea is a state-dependent disease. One of the key factors that triggers upper airway collapse is decreased pharyngeal dilator muscle activity during sleep. To date, there have not been effective methods to reverse pharyngeal hypotonia pharmacologically in sleeping human...

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Detaylı Bibliyografya
Yayımlandı:Am J Respir Crit Care Med
Asıl Yazarlar: Taranto-Montemurro, Luigi, Edwards, Bradley A., Sands, Scott A., Marques, Melania, Eckert, Danny J., White, David P., Wellman, Andrew
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Thoracic Society 2016
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074653/
https://ncbi.nlm.nih.gov/pubmed/26967681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201511-2172OC
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