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Desipramine Increases Genioglossus Activity and Reduces Upper Airway Collapsibility during Non-REM Sleep in Healthy Subjects

Rationale: Obstructive sleep apnea is a state-dependent disease. One of the key factors that triggers upper airway collapse is decreased pharyngeal dilator muscle activity during sleep. To date, there have not been effective methods to reverse pharyngeal hypotonia pharmacologically in sleeping human...

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Bibliografski detalji
Izdano u:Am J Respir Crit Care Med
Glavni autori: Taranto-Montemurro, Luigi, Edwards, Bradley A., Sands, Scott A., Marques, Melania, Eckert, Danny J., White, David P., Wellman, Andrew
Format: Artigo
Jezik:Inglês
Izdano: American Thoracic Society 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074653/
https://ncbi.nlm.nih.gov/pubmed/26967681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201511-2172OC
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