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Sequence and functional expression in Xenopus oocytes of a human insulinoma and islet potassium channel.

Regulation of insulin secretion involves the coordinated control of ion channels in the beta-cell membrane. We have isolated and characterized cDNA and genomic clones encoding a voltage-dependent K+ channel isoform expressed in human islets and in a human insulinoma. This K+ channel isoform, designa...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Philipson, L H, Hice, R E, Schaefer, K, LaMendola, J, Bell, G I, Nelson, D J, Steiner, D F
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50746/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1986382/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.1.53
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