Adenoviral-mediated transfer of the human endothelial nitric oxide synthase gene reduces acute hypoxic pulmonary vasoconstriction in rats.

Nitric oxide (NO), a vasodilator involved in the regulation of pulmonary vascular tone, is synthesized by a family of enzymes, nitric oxide synthases (NOS). To investigate whether adenoviral-mediated overexpression of constitutive endothelial NOS (ceNOS) would attenuate hypoxic pulmonary vasoconstri...

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Detalles Bibliográficos

Publicado en:	J Clin Invest
Principais autores:	Janssens, S P, Bloch, K D, Nong, Z, Gerard, R D, Zoldhelyi, P, Collen, D
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Clinical Investigation 1996
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507433/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8755640/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118795
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