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Detection of molecular signatures of oral squamous cell carcinoma and normal epithelium – application of a novel methodology for unsupervised segmentation of imaging mass spectrometry data

Intra‐tumor heterogeneity is a vivid problem of molecular oncology that could be addressed by imaging mass spectrometry. Here we aimed to assess molecular heterogeneity of oral squamous cell carcinoma and to detect signatures discriminating normal and cancerous epithelium. Tryptic peptides were anal...

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Detalhes bibliográficos
Publicado no:Proteomics
Main Authors: Widlak, Piotr, Mrukwa, Grzegorz, Kalinowska, Magdalena, Pietrowska, Monika, Chekan, Mykola, Wierzgon, Janusz, Gawin, Marta, Drazek, Grzegorz, Polanska, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5074322/
https://ncbi.nlm.nih.gov/pubmed/27168173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.201500458
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