NMR and molecular modeling evidence for a G.A mismatch base pair in a purine-rich DNA duplex.
1H NMR experiments indicate that the oligomer 5'-d(ATGAGCGAATA) forms an unusual 10-base-pair duplex with 4 G.A base pairs (underlined) and a 3' unpaired adenosine. NMR results indicate that guanosine imino protons of the G.A mismatches are not hydrogen bonded but are stacked in the helix. A G----I...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1991
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50740/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1986374/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.1.26 |
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