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Proadrenomedullin NH2-terminal 20 peptide inhibits the voltage-gated Ca2+ channel current through a pertussis toxin-sensitive G protein in rat pheochromocytoma-derived PC 12 cells.

The effect of proadrenomedullin NH2-terminal 20 peptide (PAMP) on the voltage-gated Ca2+ channel current was investigated using the perforated whole-cell clamp technique on NGF-treated PC12 cells. PAMP inhibited the Ba2+ current through N-type Ca2+ channels in a concentration dependent manner. Injec...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Takano, K, Yamashita, N, Fujita, T
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507394/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8690785/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118758
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