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Circulating microparticles in severe pulmonary arterial hypertension increase intercellular adhesion molecule-1 expression selectively in pulmonary artery endothelium

BACKGROUND: Microparticles (MPs) stimulate inflammatory adhesion molecule expression in systemic vascular diseases, however it is unknown whether circulating MPs stimulate localized ICAM-1 expression in the heterogeneically distinct pulmonary endothelium during pulmonary arterial hypertension (PAH)....

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Detalhes bibliográficos
Publicado no:Respir Res
Main Authors: Blair, Leslie A., Haven, April K., Bauer, Natalie N.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073933/
https://ncbi.nlm.nih.gov/pubmed/27765042
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-016-0445-1
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