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Effects of Rho1, a small GTPase on the production of recombinant glycoproteins in Saccharomyces cerevisiae
BACKGROUND: To humanize yeast N-glycosylation pathways, genes involved in yeast specific hyper-mannosylation must be disrupted followed by the introduction of genes catalyzing the synthesis, transport, and addition of human sugars. However, deletion of these genes, for instance, OCH1, which initiate...
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| Publicado no: | Microb Cell Fact |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5073930/ https://ncbi.nlm.nih.gov/pubmed/27769287 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12934-016-0575-7 |
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