Estimating the population abundance of tissue-infiltrating immune and stromal cell populations using gene expression

We introduce the Microenvironment Cell Populations-counter (MCP-counter) method, which allows the robust quantification of the absolute abundance of eight immune and two stromal cell populations in heterogeneous tissues from transcriptomic data. We present in vitro mRNA mixture and ex vivo immunohis...

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Detalhes bibliográficos
Publicado no:Genome Biol
Main Authors: Becht, Etienne, Giraldo, Nicolas A., Lacroix, Laetitia, Buttard, Bénédicte, Elarouci, Nabila, Petitprez, Florent, Selves, Janick, Laurent-Puig, Pierre, Sautès-Fridman, Catherine, Fridman, Wolf H., de Reyniès, Aurélien
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2016
Assuntos:
Method
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073889/
https://ncbi.nlm.nih.gov/pubmed/27765066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13059-016-1070-5
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