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Lack of interaction between ErbB2 and insulin receptor substrate signaling in breast cancer
BACKGROUND: ErbB2 Receptor Tyrosine Kinase 2 (ErbB2, HER2/Neu) is amplified in breast cancer and associated with poor prognosis. Growing evidence suggests interplay between ErbB2 and insulin-like growth factor (IGF) signaling. For example, ErbB2 inhibitors can block IGF-induced signaling while, conv...
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| Pubblicato in: | Cell Commun Signal |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
BioMed Central
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5073819/ https://ncbi.nlm.nih.gov/pubmed/27765041 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-016-0148-8 |
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