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Lack of interaction between ErbB2 and insulin receptor substrate signaling in breast cancer

BACKGROUND: ErbB2 Receptor Tyrosine Kinase 2 (ErbB2, HER2/Neu) is amplified in breast cancer and associated with poor prognosis. Growing evidence suggests interplay between ErbB2 and insulin-like growth factor (IGF) signaling. For example, ErbB2 inhibitors can block IGF-induced signaling while, conv...

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Podrobná bibliografie
Vydáno v:Cell Commun Signal
Hlavní autoři: Farabaugh, Susan M., Chan, Bonita T., Cui, Xiaojiang, Dearth, Robert K., Lee, Adrian V.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073819/
https://ncbi.nlm.nih.gov/pubmed/27765041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-016-0148-8
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