Responses of single germinal-center B cells in T-cell-dependent microculture.
B cells purified from the germinal centers (GCs) of murine Peyer's patches can be stimulated in a clonal microculture containing helper T cells and dendritic cells to divide and secrete immunoglobulin. Intraclonal isotype switching occurs, and a variety of immunoglobulin isotypes, including IgA, is...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
1991
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50737/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1824722/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.1.11 |
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