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Mechanism of cytokine-induced modulation of beta-adrenoceptor responsiveness in airway smooth muscle.

To elucidate the role of specific proinflammatory cytokines in regulating airway responsiveness, we examined the effects and mechanisms of action of IL-1beta, TNF-alpha, and IL-2 on the beta-adrenoceptor- and postreceptor-coupled transmembrane signaling mechanisms regulating relaxation in isolated r...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Hakonarson, H, Herrick, D J, Serrano, P G, Grunstein, M M
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 1996
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507346/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8647953/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118708
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