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Bruton's Tyrosine Kinase: From X-Linked Agammaglobulinemia Toward Targeted Therapy for B-Cell Malignancies

Discovery of Bruton's tyrosine kinase (BTK) mutations as the cause for X-linked agammaglobulinemia was a milestone in understanding the genetic basis of primary immunodeficiencies. Since then, studies have highlighted the critical role of this enzyme in B-cell development and function, and part...

詳細記述

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書誌詳細
出版年:J Clin Oncol
主要な著者: Ponader, Sabine, Burger, Jan A.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Clinical Oncology 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073382/
https://ncbi.nlm.nih.gov/pubmed/24778403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2013.53.1046
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