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Kinesin-5 Contributes to Spindle-length Scaling in the Evolution of Cancer toward Metastasis

During natural evolution, the spindles often scale with cell sizes to orchestrate accurate chromosome segregation. Whether in cancer evolution, when the constraints on genome integrity are relaxed, cancer cells may evolve the spindle to confer other advantages has not been investigated. Using invasi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yang, Ching-Feng, Tsai, Wan-Yu, Chen, Wei-An, Liang, Kai-Wen, Pan, Cheng-Ju, Lai, Pei-Lun, Yang, Pan-Chyr, Huang, Hsiao-Chun
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5073351/
https://ncbi.nlm.nih.gov/pubmed/27767194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35767
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