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Optical manipulation of the alpha subunits of heterotrimeric G proteins using photoswitchable dimerization systems
Alpha subunits of heterotrimeric G proteins (Gα) are involved in a variety of cellular functions. Here we report an optogenetic strategy to spatially and temporally manipulate Gα in living cells. More specifically, we applied the blue light-induced dimerization system, known as the Magnet system, an...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5073340/ https://ncbi.nlm.nih.gov/pubmed/27767077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep35777 |
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