The alpha1beta1 integrin is expressed during neointima formation in rat arteries and mediates collagen matrix reorganization.

Remodeling of the extracellular matrix by activated mesenchymal cells (myofibroblasts) is a critical aspect of wound repair in all adult organs. Collagen-dependent gel contraction, a process requiring integrin function, is an established in vitro assay thought to mimic in vivo matrix remodeling. Num...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Gotwals, P J, Chi-Rosso, G, Lindner, V, Yang, J, Ling, L, Fawell, S E, Koteliansky, V E
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1996
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507331/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8647938/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118693
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