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Elafin, a serine elastase inhibitor, attenuates post-cardiac transplant coronary arteriopathy and reduces myocardial necrosis in rabbits afer heterotopic cardiac transplantation.

We have related experimentally induced post-cardiac transplant coronary arteriopathy to increased elastolytic activity, IL-1beta, fibronectin-mediated inflammatory and smooth muscle cell (SMC) migration, and SMC proliferation. Since our in vitro studies show that a serine elastase releases SMC mitog...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Cowan, B, Baron, O, Crack, J, Coulber, C, Wilson, G J, Rabinovitch, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1996
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC507330/
https://ncbi.nlm.nih.gov/pubmed/8647937
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