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Fibrin deposition in tissues from endotoxin-treated mice correlates with decreases in the expression of urokinase-type but not tissue-type plasminogen activator.

The primary hypothesis of this report is that the formation and subsequent removal of fibrin in specific tissues during pathologic processes reflects temporal changes in the local expression of key procoagulant and fibrinolytic genes. To begin to test this hypothesis, we have used quantitative PCR a...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Yamamoto, K, Loskutoff, D J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC507329/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8647936/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI118691
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